Umbilical Cord Blood Derived Endothelial Progenitor Cells: Isolation, Characterization, and Adhesion Potential In Vitro and In Vivo by
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چکیده
Umbilical Cord Blood Derived Endothelial Progenitor Cells: Isolation, Characterization, and Adhesion Potential In Vitro and In Vivo by Melissa Ann Brown Department of Biomedical Engineering Duke University Date:_______________________ Approved: ___________________________ George Truskey, Supervisor ___________________________ William M. Reichert ___________________________ Bruce Klitzman ___________________________ Morton Friedman ___________________________ Neil Freedman An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biomedical Engineering in the Graduate School of Duke University 2009 Copyright by Melissa Ann Brown 2009
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3D study of capillary network derived from human cord blood mesenchymal stem cells and differentiated into endothelial cell with VEGFR2 protein expression
New blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ECs) which in turn give rise to primitive capillary network. Human cord blood (HCB) contains large subsets of mononuclear cells (MNCs) that can be differentiated into endothelial-like cells in vitro. Human mononuclear progenitor cells were purified from fresh umb...
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